美国科罗拉多大学安舒茨医学院招聘博士后—胎儿治疗的前沿研究

美国科罗拉多大学安舒茨医学院招聘博士后—胎儿治疗的前沿研究

Post-Doctoral Fellow

University of Colorado Anschutz Medical Campus

in Aurora, CO

Type: Full-Time

Salary: $62,232 - $70,344 per year

Posted: 11/01/2025

Category: Biochemistry and Molecular Biology

Post-Doctoral Fellow

Post-Doctoral Fellow - 38161 Faculty Description

University of Colorado Anschutz Medical Campus

Department: Surgery

Job Title: Post-Doctoral Fellow

Position #: 00839663 - Requisition #:38161Job Summary:

The Derderian Lab in the Department of Surgery at the University of Colorado  School of Medicine is seeking a highly motivated Postdoctoral Fellow to join our  team at the forefront of fetal therapy research. Our lab tackles two  transformative areas of investigation: (1) understanding placental biology and  epigenetic regulation of trophoblast invasion, with a focus on extracellular  vesicle-mediated microRNA signaling in fetal growth restriction, and (2)  pioneering in utero gene editing approaches to correct genetic disease before  birth. Current projects include the development of CRISPR-Cas9-based base  editing platforms delivered by AAV vectors and lipid nanoparticles to treat  Ornithine Transcarbamylase (OTC) deficiency in utero.

This is an exciting opportunity to contribute to a field on the cusp of major  breakthroughs. The fetal environment is rapidly emerging as the next frontier  for gene and small-molecule therapies, and fellows in our lab will gain hands-on  experience in shaping this future. By bridging basic science discovery with  translational application, this role offers the chance to work on high-impact  projects with direct relevance to maternal-fetal medicine and pediatric  surgery.

Key Responsibilities:

Design and conduct independent research projects in placental biology or in  utero gene editing.

Develop and optimize CRISPR-Cas9 base editing strategies, including plasmid  and sgRNA design.

Perform molecular and cellular assays to investigate gene regulation,  extracellular vesicle signaling, and therapeutic efficacy.

Analyze and interpret data, prepare manuscripts for publication, and  contribute to grant applications.

Collaborate with a multidisciplinary team of surgeons, geneticists, and  molecular biologists.

Mentor graduate students, residents, and junior trainees in the lab.

Present research findings at departmental seminars and national/international  conferences.Work Location:

Onsite - this role is expected to work onsite and is located at the Anschutz  Medical Campus in Aurora, Colorado

Why Join Us:

The Department of Surgery at the University of Colorado is nationally  recognized for innovation, collaboration, and commitment to advancing surgical  science. As part of the Colorado Fetal Care Center and a thriving academic  medical environment, our fellows have access to world-class core facilities,  interdisciplinary collaborations, and strong mentorship for career development.  This position offers an exceptional opportunity to build a research portfolio in  translational science with clear relevance to maternal-fetal medicine and  pediatric surgery.

Why work for the University?

The University of Colorado offers a comprehensive benefits package. To see  what benefits are available for Post-Doctoral Fellows, please visit:

Payroll & Benefits Orientation for Post-Doctoral Fellows | University of  Colorado (cu.edu)

benefits guide cover-post-doc-2024 (cu.edu)Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of hire.

Ph.D. in molecular biology, genetics, developmental biology, biomedical  sciences, or a related field.

Strong record of research productivity demonstrated by publications in  peer-reviewed journals.

Please be advised that this position is not eligible now or in the future for  visa sponsorship.

Preferred Qualifications:

Prior postdoctoral training experience (1-4 years preferred).

Expertise in CRISPR-Cas9 technology, including plasmid design and single  guide RNA development.

Background in placental biology, extracellular vesicle biology, or epigenetic  regulation.

Experience with viral vector or lipid nanoparticle development and  delivery.

Strong data analysis, communication, and scientific writing skills.

Knowledge, Skills and Abilities:

Deep understanding of molecular biology, gene regulation, and/or genome  editing technologies.

Proficiency with experimental design, data analysis, and interpretation of  complex biological datasets.

Ability to work independently while also contributing to a highly  collaborative, multidisciplinary team.

Strong written and verbal communication skills, with the ability to prepare  scientific manuscripts, grants, and presentations.

Creative problem-solving skills and the flexibility to adapt to evolving  research directions in a rapidly changing field.

Demonstrated ability to mentor and train junior researchers, graduate  students, or medical trainees.

Commitment to rigor, reproducibility, and ethical conduct of research.

Enthusiasm for translational science and the potential to move discoveries  from the lab toward clinical application.How to Apply:

For full consideration, please submit the following  document(s):

1. A letter of interest describing relevant job experiences as they relate to  listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Five professional references including name, address, phone number (mobile  number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Chris Derderian, MD at  christopher.derderian@ch ildrenscolorado.orgScreening of Applications  Begins:

Immediately and continues until position is filled. For best consideration,  apply by December 1, 2025.Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been  established as HIRING RANGE:$62,232 to $70,344 (following NRSA salary scale)

The above salary range (or hiring range) represents the University's good  faith and reasonable estimate of the range of possible compensation at the time  of posting. This position is not eligible for overtime compensation unless it is  non-exempt.

Your total compensation goes beyond the number on your paycheck. The  University of Colorado provides generous leave, health plans and retirement  contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

Equal Employment Opportunity Statement:

The University of Colorado (CU) is an Equal Opportunity Employer and complies  with all applicable federal, state, and local laws governing nondiscrimination  in employment. We are committed to creating a workplace where all individuals  are treated with respect and dignity, and we encourage individuals from all  backgrounds to apply, including protected veterans and individuals with  disabilities.ADA Statement:

The University will provide reasonable accommodations to applicants with  disabilities throughout the employment application process. To request an  accommodation pursuant to the Americans with Disabilities Act, please contact  the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu.Background  Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a  safe and secure environment for our faculty, staff, students and visitors. To  assist in achieving that goal, we conduct background investigations for all  prospective employees.Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and  other vaccine preventable diseases. If you work, visit, or volunteer in  healthcare facilities or clinics operated by our affiliated hospital or clinical  partners or by CU Anschutz, you will be required to comply with the vaccination  and medical surveillance policies of the facilities or clinics where you work,  visit, or volunteer, respectively. In addition, if you work in certain research  areas or perform certain safety sensitive job duties, you must enroll in the  occupational health medical surveillance program.

Qualifications

Application Materials Required: Cover Letter, Resume/CV, List of  References

Job Category: Faculty Primary

Location: Aurora Department: U0001 -- Anschutz Med Campus or Denver - 20324 -  SOM-SRG-PEDS Clinical

Schedule: Full-time

Posting Date: Oct 31, 2025

Unposting Date: Ongoing

Posting Contact Name: Chris Derderian

Posting Contact Email: christopher.derderian@ch ildrenscolorado.org

Position Number: 00839663

To apply, visit  https://cu.taleo.net/careersection/2/jobdetail.ftl?job=38161&lang=en

jeid-da99c30e9b7ed645 bf5f33a7894b7e2f

准备申请国外博士后的各位老师注意了！知识人网（www.zsrw.cn）小编每周定时更新最新的国内外博士后招聘信息以及访问学者、博士后资讯，感谢大家的关注！