深圳医学科学院Alexey Amunts课题组招聘公告

发布时间：2026-08-31

截止日期：详见正文

学历要求：博士研究生

所属省份：

广东

工作地点：

深圳

Amunts课题组丨The Amunts Lab

深圳医学科学院Amunts课题组现面向社会公开招聘博士后。

The Amunts Lab at the Shenzhen Medical Academy of Research and Translation is now recruiting Associate Investigators/Assistant Investigators, Postdoctoral Fellows, Research Assistants, and Laboratory Managers.

线粒体是细胞能量转换的核心，其精密功能与其复杂的内部结构密不可分。线粒体内膜折叠成嵴，为氧化磷酸化等的大分子复合物提供了动态子组织平台。尽管冷冻电镜的革命性进展已提供了体外纯化的呼吸链复合物的原子级分辨率视图，但一个根本问题依然悬而未决：这些分子机器在天然膜环境中是如何被组织、调控并发生功能性重塑的？我们仍然缺乏对这些复合物的纳米尺度排列和精确构象动态如何决定细胞器功能，以及功能失调下它们如何导致细胞衰退的机制性理解。

Mitochondria are central to the cellular architects of cellular energy conversion, and their function is linked to their intricate internal structure. The inner mitochondrial membrane is folded into cristae, dynamic subcompartments that organize the oxidative phosphorylation. Advances in Cryo-EM have provided atomic views of isolated respiratory complexes, yet a fundamental question remains unresolved: how these machines are organized, regulated, and remodeled within native membranes. We lack a mechanistic understanding of how the nanoscale arrangement and conformational dynamics within cristae dictate organelle function and how their disruption contributes to cellular decline.

Amunts博士团队旨在打破细胞原位结构研究的分辨率极限。团队目标是在原位、以更高分辨率解析线粒体能量转换系统，并捕获其在不同功能状态下的结构。我们的核心假设为，衰老与疾病中的线粒体功能的丧失直接由超分子复合物的解体和特定功能关键构象状态的缺失所决定，而这些结构特征只能在原位捕获。团队进一步提出假说：嵴的形成本身，正是由这些能量转换复合体按顺序组装成特定的寡聚阵列的过程所驱动并协调的。

Amunts Lab aims to overcome this limitation by resolving mitochondrial energy-converting complexes in-situ and at higher resolution across defined functional states. Our central hypothesis is that the mitochondrial dysfunction in aging and disease is driven by the disassembly of supramolecular complexes and the loss of specific, functionally critical conformational states that are only observable in their native cellular context. We further hypothesize that cristae formation is orchestrated through ordered assembly of these complexes into defined oligomeric arrays.

Alexey Amunts博士于2026年1月加入深圳医学科学院，任生物构造与互作研究所资深研究员。2015年，Amunts 博士在斯德哥尔摩大学建立独立的课题组，并获终身副教授职位。Amunts团队结合实验与计算研究方法，在分子和细胞层面上研究蛋白质合成与能量转化的机制，并探索这些过程在自然选择和人类疾病的演变。此外，Amunts 博士主导了瑞典国家冷冻电镜设施的创立。2024年，Amunts 博士在西湖大学进行学术休假期间，并受聘为华中农业大学与山东大学荣誉讲席教授。Amunts 博士任马克斯·普朗克分子生理学研究所的洪堡学者，兼任明斯特大学研究组组长。

Dr. Alexey Amunts joined the Institute of Bio-Architecture and Bio-Interaction (IBABI) in Shenzhen Medical Academy of Research and Translation in January 2026.  In 2015, Dr. Amunts established an independent research group at Stockholm University, where he became a tenured Associate Professor. His team investigates the molecular mechanisms of bioenergetics and protein synthesis, combining experimental and computational approaches to study energy conversion from the molecular to the cellular level, and how these processes are shaped by evolution and human disease. Dr. Amunts also played a leading role in founding the Swedish National Cryo-EM Facility. In 2024, he took a sabbatical at Westlake University, and was appointed Honorary Chair Professor at Huazhong Agricultural University and Shandong University. He is a Humboldt Scholar at the Max Planck Institute of Molecular Physiology in Dortmund and serves as a group leader at the University of Münster.

“Hire very smart people. Leave them alone, but with a tea room to talk. Support them so they have time & aren’t chasing money.”——Max Perutz。如果您有兴趣在这样的环境中工作，请联系Alexey Amunts。

博士后（3名）

Postdoctoral Fellow (3 positions)

工作内容

Job Responsibilities

1.在课题组长指导下开展独立或合作科研工作；

Conduct independent or collaborative research under the guidance of the Principal Investigator (PI);

2.协助申请各类科研项目；

Assist in applying for various research projects;

3.协助指导学生。

Assist in supervising and mentoring students.

应聘条件

Requirements

1.在国内外已取得结构生物学博士学位，具有结构生物学背景；

Hold a Ph.D. degree in structural biology;

2.在本专业领域发表或即将发表研究论文，具有独立开展科研工作的能力；

Have published or are about to publish research papers in relevant academic fields, and possess the ability to carry out independent research;

3.具有良好的英文文献阅读和写作能力；

Have good command of English for reading and academic writing;

4.具有良好沟通能力和团队协作能力、优良学术道德、强烈探索兴趣。

Possess excellent communication and teamwork skills, high academic integrity, a rigorous scientific attitude, and strong research motivation.

福利待遇

Benefits

1.按照本单位薪酬体系，提供具有市场竞争力的薪酬福利待遇，具体薪酬根据应聘者资历和成果面议；

Provide a competitive salary and benefits package based on the institute’s compensation system, with specific pay determined according to the candidate’s qualifications and achievements;

2.享受国家规定的相关福利，享受带薪年休假、员工体检等；

Enjoy statutory benefits, paid annual leave, regular health check-ups, and other employee welfare programs;

3.提供良好科研训练和科研环境；

Provide excellent research training and a supportive research environment;

4.若符合相关规定，可协助申请相关人才补助及相关配套待遇。

For qualified candidates, assistance will be provided in applying for relevant talent subsidies and supporting programs.

应聘材料及方式

Application Materials and Process

应聘者请提供以下材料

Applicants should provide

1.完整的个人中文或英文简历，包括教育背景、科研经历及成果、主要科研技能、所获奖项、个人科研兴趣等；

A complete CV in Chinese or English, including educational background, research experience and achievements, key scientific skills, awards, and personal research interests;

2.请邀请3位推荐人发送推荐信（仅副研究员/助理研究员、博士后需提供，请应聘者在应聘邮件中注明推荐人信息，并由推荐人直接将推荐信发送至amuntslab@smart.org.cn）；

Three recommendation letters (required only for Associate Investigator/Assistant Investigator and Postdoctoral Fellow applicants). The applicant should include the referees’ information in the application email, and the referees should send the recommendation letters directly to amuntslab@smart.org.cn;

3.其它能够说明科研和工作能力的材料。

Other materials that can demonstrate the applicant’s research and professional capabilities.

应聘者请将PDF版应聘材料作为附件发送至：amuntslab@smart.org.cn（邮件主题请注明“应聘岗位－姓名－专业”），待审核后会尽快安排时间面试。

Please send the application materials in PDF format to amuntslab@smart.org.cn (Email subject: “Position – Name – Major”). Qualified candidates will be notified for an interview.

应聘材料予以保密，待遇面议。

All applications will be kept confidential, and compensation is negotiable.

本招聘信息在职位未满前长期有效。

This recruitment notice remains open until all positions are filled.

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