美国阿拉巴马大学伯明翰分校招聘博士后—胶质母细胞瘤（GBM）进展机制及治疗耐药性

美国阿拉巴马大学伯明翰分校招聘博士后—胶质母细胞瘤（GBM）进展机制及治疗耐药性

Postdoctoral - PF1041P

University of Alabama at Birmingham

in Birmingham, AL

Type: Full-Time

Posted: Today

Application Due: Open Until Filled

Category: Medical Research

Job Title

Postdoctoral

Department Name

392303040 Neuropathology

School/College: Academic Joint Departments

Job Description

The Comba Laboratory in the Department of Pathology, Division of Neuropathology, at the University of Alabama at Birmingham (UAB) is seeking a highly motivated and creative postdoctoral researcher to join our multidisciplinary team investigating the mechanisms of glioblastoma (GBM) progression and therapeutic resistance.

Our research focuses on understanding how interactions between glioma cells and the brain microenvironment drive tumor invasion, recurrence, and treatment resistance. We combine cancer biology, neuroscience, extracellular matrix biology, spatial transcriptomics, advanced imaging, and immunology to identify novel therapeutic strategies for malignant brain tumors.

The successful candidate will have access to a highly collaborative research environment and state-of-the-art technologies, including patient-derived glioblastoma models, orthotopic mouse models, 3D organotypic brain slice cultures, live-cell imaging approaches, multiplex immunofluorescence, RNAscope, spatial transcriptomics (10x Visium HD, Xenium), flow cytometry, and bioinformatics analyses.

The Comba Laboratory collaborates extensively with investigators across the UAB O'Neal Comprehensive Cancer Center, the Department of Neurosurgery, the Department of Pathology, and national and international leaders in neuro-oncology, extracellular matrix biology, neuroscience, and spatial biology.

Applications containing a cover letter and current curriculum vitae should be sent to: Andrea Comba via email: andraecomba@uabmc.edu

Required Qualifications

PostdocCandidates should possess a Ph.D., M.D., or equivalent degree in cancer biology, neuroscience, molecular biology, genetics, computational biology, or related biomedical fields. Candidates should have experience with cell culture, animal models, molecular biology, imaging, or computational analysis. Experience with 3D organoids or slices models, confocal imaging and Bioinformatics analysis is desirable. We are seeking individuals who are enthusiastic and collaborative.

Interested candidates should submit CV, a cover letter detailing research experience and contact details of three references to: Andrea Comba via email: andraecomba@uabmc.edu

Open Date: 06/25/2026

Open Until Filled: Yes

Nondiscrimination Statement

UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.

Pre-employment Background Check

A pre-employment background check investigation is performed on candidates selected for employment.

About University of Alabama at Birmingham

The University of Alabama at Birmingham is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 250 postdocs are currently training in a variety of disciplines, including but not limited to engineering, medicine, natural sciences & mathematics, public health, and optometry.

The UAB Office of Postdoctoral Education and the UAB Postdoc Association work together to develop career opportunities that enhance and define the training experience for all postdoctoral scholars at UAB.

Because of its commitment to the success of postdoctoral fellows, UAB ranks consistently as one of the top locations among US universities for training postdoctoral scholars.

Department of Pathology

University of Alabama at Birmingham

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