美国波士顿儿童医院Springer实验室特聘博士后—细胞表面受体、整合素激动剂与类器官生物学

美国波士顿儿童医院Springer实验室特聘博士后—细胞表面受体、整合素激动剂与类器官生物学

Special Postdoctoral Fellow in Cell Surface Receptors, Integrin Agonists, and Organoid Biology

Employer

Springer Lab at BCH

Location

Boston, Massachusetts (US)

Salary

$78,000/annually + benefits

Closing date

Apr 25, 2026

Discipline

Life Sciences, Biotechnology, Cell Biology, Molecular Biology

Position Type

Full Time

Job Type

Postdoc

Organization Type

Academia

Job Details

Join the Lab of Tim Springer

Tim Springer, a leader in integrin biology, invites aspiring scientists to join his lab to advance groundbreaking research at the intersection of integrin signaling, organoid development, and cell surface receptor structure and mechanobiology. A new focus is bioengineering new materials for organoids, with wide-reaching implications for regenerative medicine, stem cell biology, and therapeutic development. This role offers mentorship and unique opportunities to establish a strong scientific foundation for launching an independent research career.

About the Role:

As a Special Postdoctoral Fellow, you will:

Pursue cutting-edge research in areas such as:

Stem Cells and organoids: Develop and apply novel ligands that bind to temperature-dependent gels for stem cell and organoid growth

Cryo-EM: Activation of integrins and TGF-β and ligand binding

Mechanobiology: Integrin force transduction in adhesion and TGF-β activation

Single Molecules: Utilize advanced techniques including FRET and magnetic tweezers to explore conformational change kinetics and force transmission in integrins and selectins

Innovative ReaLiSM: (Receptor and Ligand in Single Molecules) to study receptor-ligand binding dynamics

TGF-β Activation: Research localized activation at cell surfaces for new therapeutic targets

Own and Develop Your Project: We encourage candidates to develop new research ideas, which they can carry forward to establish their own labs.

Key Techniques and Approaches:

Organoid and stem cell systems

Single-molecule imaging

Cryo-EM

FRET reporters using non-canonical amino acids

Magnetic and laser tweezers

Mechanobiology and therapeutic target discovery

Why Join Us?

Mentorship from Tim Springer, renowned for his pioneering work in integrins and cell biology

Work at the frontier of a rapidly expanding area bridging fundamental biophysics and translational biotech

Independence and Growth: Develop projects that will empower your transition to an independent research career

Collaborative environment at Harvard Medical School and Boston Children’s Hospital

Application Details:

To apply, please email the following to springer_jobs@crystal.harvard.edu with "Special Postdoctoral Fellow" in the subject line:

Cover letter (include a brief outline of your project interests)

CV

Three references

Salary: $78,000 annually

Appointment: 1-year initial term, renewable (multi-year funding)

Start: Summer-Fall 2026

Visa sponsorship: Available

Qualified applicants will receive consideration without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status, or disability.

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