美国凯斯西储大学博士后职位—膜蛋白结构生物学与生理学

美国凯斯西储大学博士后职位—膜蛋白结构生物学与生理学

Postdoctoral Position in Membrane Protein Structural Biology and Physiology

Date Posted: Posted on 3 June 2025

Location: United States (US)

Case Western Reserve University

The laboratory of Dr. Nami Tajima at Case Western Reserve University School of Medicine invites applications for a postdoctoral researcher to investigate the molecular mechanisms of ligand-gated ion channel signaling complexes. We seek a highly motivated, creative, and collaborative individual with expertise in electrophysiology, structural biology, or related fields.

Research Focus

Our lab is broadly interested in understanding:

The regulatory mechanisms of ion channels involved in fundamental brain function and neurological disorders.

The signaling networks and protein-protein interactions that govern synaptic transmission.

Structure-based drug discovery targeting ion channel complexes.

We employ a multidisciplinary approach that integrates Cryo-EM, X-ray crystallography, electrophysiology, molecular and cellular biology, biochemistry, and biophysics.

Our lab has full access to state-of-the-art structural biology facilities, including a Glacios equipped with Seletrix Energy filter and Falcon IV DED camera,Titan Krios with BioQuantum K3, and Volta Phase Plate, Aquilos II Cryo-FIB with CLEM system, and Tecnai T12&TF20.

Qualifications

Candidates must hold (or be close to completing) a Ph.D. obtained within the past three years in a relevant field such as structural biology, biophysics, neuroscience, or molecular biology. A strong publication record and prior experience in one or more of the following areas is highly desirable:

Electrophysiology

Biochemistry or protein purification

Cryo-EM or X-ray crystallography

Neuroscience or cell biology

Mass spectrometry

In vitro and in vivo fluorescence imaging

How to Apply

Interested applicants should send the following materials to Dr. Nami Tajima at [Please click the Apply button for the link or address]: (1) a cover letter describing research interests and career goals, (2) a current CV, and (3) contact information for 2–3 references.

We look forward to hearing from passionate researchers eager to explore the structure and function of ion channels in the brain.

Follow the link for more details:

https://www.the-tajima-lab-at-cwru.com/

https://physiology.case.edu/people/faculty/nami-tajima/

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