杜克大学生物化学、化学、分子生物学、医学博士后招聘

　　杜克大学生物化学、化学、分子生物学、医学博士后招聘

　　Job Description

　　POSTDOCTORAL FELLOW POSITION Starting on or after November 1, 2019 to study the role of TGF-beta superfamily signaling pathways in the tumor microenvironment and in pancreatic cancer biology, at Duke University and the Duke Cancer Institute.

　　The Blobe Lab in the Departments of Medicine, Pharmacology and Cancer Biology, at Duke University (Durham, NC) is seeking a full-time Postdoctoral fellow for basic/translational research in solid tumor cancer biology and signal transduction. We are an established lab at Duke University, investigating the role of signaling pathways and the tumor microenvironment, including the immune microenvironment, on cancer progression, with a goal of utilizing that knowledge to define new therapeutic strategies. The ideal candidate will have research laboratory experience in pre-clinical mouse models of disease and molecular and cellular biology techniques including flow-cytometry, PCR, immunoblotting, cell transfection and tissue culture. Under the direction of the Principal Investigator, the Postdoctoral fellow will conduct molecular and cellular research experiments with human and mouse specimens, and in genetically engineered murine cancer models, prepare grants and research reports and will contribute to lab maintenance and organization.

　　MAJOR RESPONSIBILITIES:

　　Carry out tissue culture, biochemical, molecular and cell biology assays including DNA/RNA extraction, purification and analysis, cell populations purification and isolation, flow-cytometry analysis, cell transfection and infection, mouse work including colony supervision and therapeutics.

　　Contribute to the development and implementation of lab protocols and organizational frameworks to create efficient lab workflows.

　　Help with day-to-day lab functions (e.g. instrument maintenance and reagent preparation).

　　Present and discuss experimental findings and plans in meetings with the Principal Investigator and research group.

　　Help ensure general lab safety standards.

　　Supervision and training of technical personnel as required.

　　Preparation of research reports and grants

　　QUALIFICATIONS:

　　Ph.D. and/or M.D. degree and job-related experience. Degrees in Biochemistry, Chemistry, Molecular Biology, Medicine or related field.

　　Experience in a cell and molecular research laboratory, particularly with cancer models.

　　Experience with tissue culture.

　　Experience with mouse models.

　　Knowledge of / experience with standard lab assays including viability/proliferation assays, immunoblotting, PCR, ELISA, microscopy and flow-cytometry.

　　Ability to work with minimal supervision.

　　Excellent communication and organizational skills.

　　Scientists wishing to join our research team will find that the cancer research community at Duke University and the Duke Cancer Institute is welcoming, diverse and supportive with opportunities for collaboration, learning and career advancement.

　　Applications should consist of a one-page cover letter and a CV including publication record, brief descriptions of previous research accomplishments and techniques, and the name and contact information for three references sent via the following web site

　　https://careers.duke.edu/job/Durham-POSTDOCTORAL-ASSOCIATE-Medical-Oncology-NC-27710/568400400/