美国凯斯西储大学招聘博士后—癌症生物学与表观遗传学

美国凯斯西储大学招聘博士后—癌症生物学与表观遗传学

Postdoctoral Fellow – Cancer Biology & Epigenetics

Case Western Reserve University

Date Posted: Posted on 3 September 2026

Location: United States (US)

Job Tags:

cancer biology, Cancer Epigenetics, postdoctoral research fellow, posttranslational modifications, rna biology

Two full-time Postdoctoral Fellow positions are available in the Dr. Wenjian Gan Lab in the department of Biochemistry at Case Western Reserve University, Cleveland, Ohio, USA. We investigate the mechanistic and physiological roles of protein post-translational modifications (PTMs)—with a focus on arginine methylation—in human cancers. Research in the lab explores how arginine methylation regulates genomic instability, cell metabolism, signal transduction, and tumor progression to identify novel druggable targets. The project employs an integrative toolkit combining protein biochemistry, molecular biology, functional cell assays, genetic mouse models, and 3D patient-derived organoids (PDOs). More details see lab website https://www.wenjianganlab.com/

Key Responsibilities

Molecular & Cellular Dissection: Execute biochemical and cell-based experiments (plasmid construction, PCR/RT-qPCR, transfections, IP/Western blot, proliferation, and colony formation assays) to map arginine methylation pathways.

In Vivo & Translational Studies: Utilize genetic mouse models and patient-derived organoid platforms to study cancer progression and metastasis, including mouse breeding/genotyping, preclinical drug dosing, and tumor progression tracking.

Scientific Communication & Grants: Co-author manuscripts and grant applications with the PI, create publication-ready figures, and present research findings in progress seminars and departmental journal clubs.

Lab Stewardship: Contribute to daily laboratory operations, including equipment maintenance, reagent/buffer preparation, inventory management, and lab upkeep.

Qualifications

Education & Experience:D. or M.D./Ph.D. in Biochemistry, Molecular/Cellular Biology, Cancer Biology, or a related discipline, earned within the last 3 years.

Technical Skills: Proven hands-on expertise in molecular biology, protein biochemistry, cell culture techniques, and mouse models. Experience with organoid culture is preferred.

Track Record: Strong background of scientific productivity evidenced by peer-reviewed publications.

Professional Attributes: Self-motivated, collaborative, organized, and driven to advance translational cancer research.

准备申请国外博士后的各位老师注意了！知识人网（www.zsrw.cn）小编每周定时更新最新的国内外博士后招聘信息以及访问学者、博士后资讯，感谢大家的关注！