瑞典哥德堡大学博士后—线粒体DNA复制与转录

瑞典哥德堡大学博士后—线粒体DNA复制与转录

Postdoctoral fellow in Mitochondrial DNA replication and transcription

University of Gothenburg (GU)

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following four departments:

The Department of Infectious Diseases

The Department of Microbiology and Immunology

The Department of Medical Biochemistry and Cell Biology

The Department of Laboratory Medicine

At present, the institute has about 360 employees and approximately 450 million SEK in total assets

Subject area

Mitochondrial DNA replication and transcription

Subject area description

Mitochondria contain their own genome that codes for several subunits of the respiratory chain. We have developed in vivo and in vitro techniques to study the basic mechanisms of human mitochondrial DNA replication and transcription, and how these processes are regulated.

Duties

With this project the candidate will investigate the biochemical mechanisms of proteins involved in mitochondrial genome replication and/or transcription. Our laboratory has identified new proteins involved in these processes, which will be examined both in vivo and in vitro using classic biochemistry, cell biology, and next generation sequencing techniques.

Eligibility

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.

Assessment criteria

We are looking for a highly motivated individual with a recent PhD and experience of in vitro biochemical characterization of purified recombinant proteins. Knowledge of mitochondrial systems and documented experience with cloning, mutagenesis, gene expression, cell culture, radiolabeled isotopes, and in vitro DNA replication and/or transcription are of merit. The work will involve collaboration both within and outside the group, and so good teamwork and communication skills are important. The candidate is expected to be enthusiastic, capable of planning and executing research independently, and to have a passion and curiosity for science. Fluent written and spoken English is required since we operate in a very international environment.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.

Employment

The employment is full time and temporary, two years with the possibility of one year’s extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information

If you have any questions about the position, please contact Maria Falkenberg, Professor, +46 (0)317863444, maria.falkenberg@medkem.gu.se

For more information about our research, please visit our webpage: www.falkenberglab.org

Unions

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande

Application

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

The application should contain:

- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying

- A detailed CV including a list of publications

- Proof of completed PhD

- Contact details of two references.

Applications must be received by: 2022-07-19

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/