美国哥伦比亚大学医学中心招收博士后

　　美国哥伦比亚大学医学中心招收博士后

　　Postdoctoral Research Scientist

　　The Herbert Irving Comprehensive Cancer Center (HICCC) at Columbia University is seeking a talented Postdoctoral Research Scientist with a PhD trained in genetic and epigenetic profiling using NGS. The lab specializes in liver biology, with a particular focus on using complementary model systems to study molecular mechanisms underlying cholestatic liver diseases, including zebrafish, mouse and in vitro cell culture systems. Research focus will be on elucidating the mechanisms driving cellular heterogeneity within cholangiocytes and how cell-type specific characteristics determine cellular behavior and disease phenotype. Studies will include cell isolation, traditional molecular techniques and assays, gene editing using CRISPR-CAS9, RNA-Seq, Epigenetic profiling, bioinformatics using both in vitro systems and whole animal models. Studies will include cell isolation, traditional molecular techniques and assays, gene editing using CRISPR-CAS9, RNA-Seq, Epigenetic profiling, bioinformatics using both in vitro systems and whole animal models. Visit the website: http://www.zhaolabcolumbia.org/

　　Minimum Degree Required:

　　- Ph.D, MD, or equivalent doctoral degree

　　Minimum Qualifications:

　　- Excellent experimental and analytic skills and willingness to learn new model system and methodologies

　　- Self-motivated with strong interest in studying the mechanistic and translational aspects of liver diseases

　　- Effective communication and writing skills and record of publication in peer-reviewed journal (s)

　　-Ability to work independently and collaboratively

　　Preferred Qualifications:

　　- Experience in genetic and epigenetic profiling using NGS

　　- Prior experience with disease modeling using mammalian models or in vitro systems and experience in NGS and bioinformatics

　　How to apply:

　　All candidates must apply through Columbia University RAPS online employment application system under Requisition Number: 00001401. Please use the following link to apply: https://pa334.peopleadmin.com/postings/5043

　　The salary of the position will be competitive based on qualifications.

　　Applicants should send a CV, a brief statement of interest, and contact information for three references.