英国伯明翰大学癌症与基因组科学研究所博士后研究员

英国伯明翰大学癌症与基因组科学研究所博士后研究员

Research Fellow - Institute Of Cancer & Genomic Sciences - 81208

University Of Birmingham

Position Details

Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences

Location: University of Birmingham, Edgbaston, Birmingham UK

Full time starting salary is normally in the range £31,406 to £40,927 with potential progression once in post to £43,434.

Grade 7

Full Time / Fixed Term Contract for up to 18 months

Closing date: 7 July 2022

Background To create and contribute to the creation of knowledge by undertaking a specified range of activities within an established research programme and/or specific research project.

To undertake structural and functional investigation of a variety of complex macromolecular interactions in the human DNA-damage response (DDR) and how they are regulated by post-translational modifications (See doi: 10.1016/j.celrep.2016.11.063, doi: 10.1016/j.celrep.2014.03.013, doi: 10.1126/science.1235822, doi: 10.1016/j.cell.2009.07.043). The research will be carried out in the laboratory of Steve Smerdon at the Institute of Cancer and Genomic Sciences located within the University of Birmingham Medical School in the UK. Experimental approaches will be structure-focused (mainly cEM) but highly multi-disciplinary and the work will benefit from close interactions with a cluster of world-class laboratories within the ICGS interested in DDR biology.

Summary of Role • Work within specified research grants and projects and contribute to writing bids • Operate within area of specialism • Analyse and interpret research findings and results • Contribute to generating funding • Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues, asset or company sales, IP generated) and/or public understanding of the discipline or similar

Main Duties / Responsibilities The responsibilities may include some but not all of the responsibilities outlined below. • Develop research objectives and proposals for own or joint research, with assistance of a mentor if required • Contribute to writing bids for research funding • Analyse and interpret data • Apply knowledge in a way which develops new intellectual understanding • Disseminate research findings for publication, research seminars etc • Supervise students on research related work and provide guidance to PhD students where appropriate to the discipline • Contribute to developing new models, techniques and methods • Undertake management/administration arising from research • Contribute to Departmental/School research-related activities and research- related administration • Contribute to enterprise, business development and/or public engagement activities of manifest benefit to the College and the University, often under supervision of a project leader • Collect research data; this may be through a variety of research methods, such as scientific experimentation, literature reviews, and research interviews • Present research outputs, including drafting academic publications or parts thereof, for example at seminars and as posters • Provide guidance, as required, to support staff and any students who may be assisting with the research • Deal with problems that may affect the achievement of research objectives and deadlines • Promotes equality and values diversity acting as a role model and fostering an inclusive working culture.

Person Specification Essential • PhD (or near to completion) in biochemistry, structural biology, biophysics or related discipline • Demonstrable experience with cEM sample preparation, data collection/processing and analysis • Good knowledge and experience in molecular biology techniques and recombinant protein production using pro- and eukaryotic expression systems • Technical expertise in biochemical and structural biology work • Track record of writing papers as evidenced by publications or submitted manuscripts • Experience of experimental design • Good oral and written communication skills evidenced by data presentation at scientific meetings • High level analytical capability • Ability to communicate complex information clearly • Fluency in relevant models, techniques or methods and ability to contribute to developing new ones • Ability to assess resource requirements and use resources effectively • Understanding of and ability to contribute to broader management/administration processes • Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly.

Proven experience in one or more of the following would be an advantage: • X-ray crystallography • Biophysical techniques for the analysis of protein-protein interactions • Basic cell biological techniques

Further particulars can be found here.

Informal enquires to Professor Steve Smerdon, email: S.J.Smerdon@bham.ac.uk

Valuing excellence, sustaining investment

We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working.

Primary Location: GB-GB-Birmingham

Job: Academic Non-clinical

Organization: Cancer and Genomic Sciences

Schedule: Temporary   Full-time

Job Posting: 16.06.2022, 6:00:00 AM

Grade (for job description): Grade 7

Salary (Pay Basis): 31,406.00

Maximum Salary: 43,434.00

Advert Close Date: 08.07.2022, 5:59:00 AM

Fixed Term Contract End Date 31.01.2024